Loonatics Unleashed is an American animated series produced by Warner Bros. Animation that ran on the Kids' WB for two seasons from 2005[1] to 2007 in the United States, Teletoon in Canada, Kids Central (now known as Okto) in Singapore, Cartoon Network's Boomerang in Australia, Cartoon Network in the UK, Italy, Southeast Asia and Latin America, and XHGC in Mexico. It is still broadcasting in reruns on the Clan channel of the Televisión Española network in Spain.

The series was based/inspired on the Looney Tunes cartoon characters, with the series described by Warner Bros. as an "action-comedy." Loonatics Unleashed is meant to be a mixture of the Looney Tunes shorts' irreverent style of humor and a modern action animated series, with the characters designed in a more action cartoon inspired style. Unlike previous Looney Tunes-related shows, Loonatics Unleashed has a darker tone and takes place in a post-apocalyptic setting, as well as multiple minor story arcs.

The Looney Tunes TV franchise went on hiatus after Loonatics Unleashed ended, until The Looney Tunes Show was released in 2011